Eli Lilly published the results of its ATTAIN-1b trial for obesity in September 2025 7 , which compared orforglipron to placebo in more than 3,100 adults without diabetes, with a BMI of 30+ or 27-30 with an obesity-related complication including hypertension, dyslipidaemia, cardiovascular disease or obstructive sleep apnoea and a history of at least one patient-reported unsuccessful dietary effort to lose body weight, who have tried unsuccessfully to lose weight with diet alone
[1] [2] Each formulation has different pharmacokinetic properties that inform perioperative management
In the SURMOUNT-5 head-to-head trial, tirzepatide produced 20.2% average weight loss versus 13.7% for semaglutide
These findings demonstrate how miRNomics integrates multiple omic layers, offering valuable insights for breeding and biofortification
Food stays in your stomach for a longer time, which gives you a feeling of fullness and reduces hunger cravings
Monitoring micronutrients in cigarette smokers